Effect of Olea europaea L. and Juglans regia L. Extracts on Human Cancer Cell Line Viability with Studying of Hypoglycemic and Antiglycation Properties

There is an urgent and continuous need to discover new sources of medicinal plants obtain useful compounds with health properties. So the purpose this study was investigate activity Olea europaea L Juglans regia leaves extract on Hela cell line viability, antidiabetic Antiglycation. The aqueous extracts were obtained from leaves. Alloxan 180 mg /kg body used induce diabetes. Mice blood glucose level ≥200 mg/dl considered as diabetic received 10 mg/kg weight Extracts. For Antiglycation, SDS-PAGE (sodium dodecyl sulphate–polyacrylamide gel electrophoresis) prepared for appearance high molecular products. cultured in RPMI-1640 medium MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay analysis. results showed that mean levels decreasing mice treated mg/Kg O. J. regia. Also better than inhibition glycation induced protein cross-linking at all studied concentrations. Cytotoxicity increased increasing doses cytotoxic effects J.regia higher O.europaea This promising results.